This literature review provides an in-depth examination of the wound healing process, focusing on the cellular and molecular aspects involved. The review highlights the exudative, proliferative, and remodeling phases of wound healing, emphasizing the role of various cells, growth factors, and cytokines. The inflammatory stage is characterized by the influx of leukocytes, which contribute to tissue repair through the release of lysosomal enzymes and reactive oxygen species. The proliferative stage involves cell proliferation, angiogenesis, and reepithelialization, with fibroblasts and endothelial cells playing crucial roles. The remodeling stage aims to achieve maximum tensile strength through the reorganization and degradation of the extracellular matrix, leading to the formation of scar tissue. The review also discusses the epithelial-mesenchymal transition (EMT) and the Hedgehog signaling pathway, which are important for tissue repair and regeneration. The Hedgehog pathway, involved in embryological development and tissue standardization, is particularly highlighted for its role in regulating angiogenesis and tissue remodeling. Overall, the review underscores the complex interplay of various biological processes and the importance of understanding these mechanisms for effective wound healing.This literature review provides an in-depth examination of the wound healing process, focusing on the cellular and molecular aspects involved. The review highlights the exudative, proliferative, and remodeling phases of wound healing, emphasizing the role of various cells, growth factors, and cytokines. The inflammatory stage is characterized by the influx of leukocytes, which contribute to tissue repair through the release of lysosomal enzymes and reactive oxygen species. The proliferative stage involves cell proliferation, angiogenesis, and reepithelialization, with fibroblasts and endothelial cells playing crucial roles. The remodeling stage aims to achieve maximum tensile strength through the reorganization and degradation of the extracellular matrix, leading to the formation of scar tissue. The review also discusses the epithelial-mesenchymal transition (EMT) and the Hedgehog signaling pathway, which are important for tissue repair and regeneration. The Hedgehog pathway, involved in embryological development and tissue standardization, is particularly highlighted for its role in regulating angiogenesis and tissue remodeling. Overall, the review underscores the complex interplay of various biological processes and the importance of understanding these mechanisms for effective wound healing.