This article reports on the controlled creation and deletion of individual magnetic skyrmions in an ultrathin magnetic film using local spin-polarized currents from a scanning tunneling microscope (STM). The external magnetic field tunes the energy landscape, and the temperature is adjusted to prevent thermally activated switching between topologically distinct states. The switching rate and direction can be controlled by the parameters used for current injection. The creation and annihilation of single magnetic skyrmions demonstrate the potential for topological charge in future information-storage concepts. The study shows that magnetic skyrmions can be manipulated individually and independently, even in close proximity to each other, making them promising candidates for spintronic applications. The mechanisms contributing to the switching process, including thermal noise, Joule heating, nonthermal excitations, and spin transfer torque (STT), are discussed, and the feasibility of using spin-polarized tunnel currents for controlled manipulation of individual skyrmions is demonstrated.This article reports on the controlled creation and deletion of individual magnetic skyrmions in an ultrathin magnetic film using local spin-polarized currents from a scanning tunneling microscope (STM). The external magnetic field tunes the energy landscape, and the temperature is adjusted to prevent thermally activated switching between topologically distinct states. The switching rate and direction can be controlled by the parameters used for current injection. The creation and annihilation of single magnetic skyrmions demonstrate the potential for topological charge in future information-storage concepts. The study shows that magnetic skyrmions can be manipulated individually and independently, even in close proximity to each other, making them promising candidates for spintronic applications. The mechanisms contributing to the switching process, including thermal noise, Joule heating, nonthermal excitations, and spin transfer torque (STT), are discussed, and the feasibility of using spin-polarized tunnel currents for controlled manipulation of individual skyrmions is demonstrated.