The study by Brotons et al. (1995) investigates the presence of estrogenic activity in foods preserved in lacquer-coated cans. Using the E-screen bioassay, the researchers found that the estrogenic activity in these foods was due to bisphenol-A, a plastic monomer identified in both the liquid and autoclaved water from the cans. The amount of bisphenol-A in the extracts accounted for all the measured hormonal activity. The study suggests that the estrogenic activity in these cans is primarily due to the leaching of bisphenol-A from the lacquer coating, rather than other xenoestrogens. The findings highlight the need for closer scrutiny of plastic coatings in food packaging to ensure consumer safety.The study by Brotons et al. (1995) investigates the presence of estrogenic activity in foods preserved in lacquer-coated cans. Using the E-screen bioassay, the researchers found that the estrogenic activity in these foods was due to bisphenol-A, a plastic monomer identified in both the liquid and autoclaved water from the cans. The amount of bisphenol-A in the extracts accounted for all the measured hormonal activity. The study suggests that the estrogenic activity in these cans is primarily due to the leaching of bisphenol-A from the lacquer coating, rather than other xenoestrogens. The findings highlight the need for closer scrutiny of plastic coatings in food packaging to ensure consumer safety.