B. pseudomallei is difficult to distinguish from B. thailandensis and B. cepacia complex using phenotypic tests. Infection with B. pseudomallei should be considered in patients with pneumonia after travel to the Baja Peninsula in Mexico, especially after extreme weather events. Due to the risk of transmission to laboratory workers and potential use in bioterrorism, clinical laboratories should perform limited testing on suspected isolates before referring them to public health labs for definitive identification. The study used the Multi-Locus Sequence Typing website for analysis. In Brazil, a Zika virus (ZIKV) outbreak occurred in Camaçari, Bahia, with symptoms including maculopapular rash, fever, myalgias, and conjunctivitis. Serum samples from 24 patients were tested for ZIKV, DENV, CHIKV, WNV, and Mayaro virus. RT-PCR detected ZIKV in 7 patients and CHIKV in 3. ZIKV sequences were found to belong to the Asian lineage and showed 99% identity with a French Polynesia isolate. Most ZIKV-positive patients were women with no history of international travel. Laboratory findings included low leukocyte and platelet counts, and elevated C-reactive protein levels. ZIKV infections were confirmed by sequencing the envelope gene. The outbreak highlights the need for laboratory confirmation of arboviral infections, as clinical and epidemiologic diagnosis may be unreliable. This study was supported by the Bahia State Research Foundation. ZIKV is a mosquito-borne flavivirus related to yellow fever, dengue, and West Nile viruses. It was first identified in Uganda in 1947 and reported in humans in 1952. Outbreaks occurred in Yap Island (2007), French Polynesia (2013–2014), and New Caledonia (2014). In Brazil, ZIKV co-circulated with DENV and CHIKV, leading to an outbreak in Camaçari. ZIKV was detected in 10 of 24 patients, with symptoms consistent with the virus. The study emphasizes the importance of laboratory confirmation for accurate diagnosis.B. pseudomallei is difficult to distinguish from B. thailandensis and B. cepacia complex using phenotypic tests. Infection with B. pseudomallei should be considered in patients with pneumonia after travel to the Baja Peninsula in Mexico, especially after extreme weather events. Due to the risk of transmission to laboratory workers and potential use in bioterrorism, clinical laboratories should perform limited testing on suspected isolates before referring them to public health labs for definitive identification. The study used the Multi-Locus Sequence Typing website for analysis. In Brazil, a Zika virus (ZIKV) outbreak occurred in Camaçari, Bahia, with symptoms including maculopapular rash, fever, myalgias, and conjunctivitis. Serum samples from 24 patients were tested for ZIKV, DENV, CHIKV, WNV, and Mayaro virus. RT-PCR detected ZIKV in 7 patients and CHIKV in 3. ZIKV sequences were found to belong to the Asian lineage and showed 99% identity with a French Polynesia isolate. Most ZIKV-positive patients were women with no history of international travel. Laboratory findings included low leukocyte and platelet counts, and elevated C-reactive protein levels. ZIKV infections were confirmed by sequencing the envelope gene. The outbreak highlights the need for laboratory confirmation of arboviral infections, as clinical and epidemiologic diagnosis may be unreliable. This study was supported by the Bahia State Research Foundation. ZIKV is a mosquito-borne flavivirus related to yellow fever, dengue, and West Nile viruses. It was first identified in Uganda in 1947 and reported in humans in 1952. Outbreaks occurred in Yap Island (2007), French Polynesia (2013–2014), and New Caledonia (2014). In Brazil, ZIKV co-circulated with DENV and CHIKV, leading to an outbreak in Camaçari. ZIKV was detected in 10 of 24 patients, with symptoms consistent with the virus. The study emphasizes the importance of laboratory confirmation for accurate diagnosis.