DeepTools is a flexible platform for exploring deep-sequencing data, offering a Galaxy-based web server with a suite of tools for processing and visualizing NGS data. The platform enables users with little bioinformatic background to explore sequencing results in a standardized setting. Users can upload pre-processed files with continuous data in standard formats and generate heatmaps and summary plots in a straightforward, yet highly customizable manner. The platform also provides tools for analyzing aligned reads and generating normalized coverage files. As a modular and open-source platform, deepTools can be easily expanded and customized to future demands. The web server is freely available at http://deeptools.ie-freiburg.mpg.de and is accompanied by extensive documentation and tutorials. The web server can be used without registration and can be installed locally either stand-alone or as part of Galaxy. The platform is designed to address the challenges of processing, analyzing, and interpreting NGS data. It includes tools for quality control, data processing, and visualization. The deepTools modules can be classified into three components: (i) global assessments of aligned reads (quality control), (ii) the generation of normalized coverage files (data extraction and reduction), and (iii) visual exploration and cluster analysis (data interpretation). The platform also includes other tools for data import, text file manipulation, genomic interval operations, and peak calling on ChIP-seq data. The platform provides extensive guidance on tool usage and NGS data analysis. It includes video tutorials, detailed case studies, FAQs, and discussion groups to support users throughout their work. The deepTools web server is available at http://deeptools.ie-freiburg.mpg.de and offers a variety of tools for visualizing and analyzing NGS data. The platform is designed to be user-friendly and integrates seamlessly with the Galaxy framework, which is one of the most popular analysis platforms for NGS data. The platform is written in Python and is available as a one-click installation for any local Galaxy instance via the Galaxy Tool Shed. The platform is also available as a stand-alone version for command line usage and free access to the code. The platform is designed to be modular and flexible, allowing for the inclusion of additional tools in future releases. The platform is based on open-source code and represents the result of a community effort, with the potential to set standards for the visualization of genome-wide data.DeepTools is a flexible platform for exploring deep-sequencing data, offering a Galaxy-based web server with a suite of tools for processing and visualizing NGS data. The platform enables users with little bioinformatic background to explore sequencing results in a standardized setting. Users can upload pre-processed files with continuous data in standard formats and generate heatmaps and summary plots in a straightforward, yet highly customizable manner. The platform also provides tools for analyzing aligned reads and generating normalized coverage files. As a modular and open-source platform, deepTools can be easily expanded and customized to future demands. The web server is freely available at http://deeptools.ie-freiburg.mpg.de and is accompanied by extensive documentation and tutorials. The web server can be used without registration and can be installed locally either stand-alone or as part of Galaxy. The platform is designed to address the challenges of processing, analyzing, and interpreting NGS data. It includes tools for quality control, data processing, and visualization. The deepTools modules can be classified into three components: (i) global assessments of aligned reads (quality control), (ii) the generation of normalized coverage files (data extraction and reduction), and (iii) visual exploration and cluster analysis (data interpretation). The platform also includes other tools for data import, text file manipulation, genomic interval operations, and peak calling on ChIP-seq data. The platform provides extensive guidance on tool usage and NGS data analysis. It includes video tutorials, detailed case studies, FAQs, and discussion groups to support users throughout their work. The deepTools web server is available at http://deeptools.ie-freiburg.mpg.de and offers a variety of tools for visualizing and analyzing NGS data. The platform is designed to be user-friendly and integrates seamlessly with the Galaxy framework, which is one of the most popular analysis platforms for NGS data. The platform is written in Python and is available as a one-click installation for any local Galaxy instance via the Galaxy Tool Shed. The platform is also available as a stand-alone version for command line usage and free access to the code. The platform is designed to be modular and flexible, allowing for the inclusion of additional tools in future releases. The platform is based on open-source code and represents the result of a community effort, with the potential to set standards for the visualization of genome-wide data.